产品货号：
Z11504
中文名称：
ARID1A抗体
英文名称：
Anti-ARID1A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARID1A Antibody |
| 指标别名 | ARID1A;B120;BAF250;BAF250a;BM029;BRG1 associated factor 250;BRG1 associated factor 250a;C1orf4;hELD;hOSA1;Osa homolog 1;OSA1;P270;SMARCF1;SWI like protein;SWI/SNF complex protein p270 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | ARID1A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ARID1A recombinant protein (Position:R857-Q1552). |
| 实际分子量 | 270KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene.This gene encodes a member of the SWI/SNF family,whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes.The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI,which is required for transcriptional activation of genes normally repressed by chromatin.It possesses at least two conserved domains that could be important for its function.First,it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus.Second,the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation.It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions.Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | O14497 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | AT-rich interaction domain 1A |
| 蛋白名全称 | AT-rich interactive domain-containing protein 1A |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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